Nanomaterials: Potential Broad Spectrum Antimicrobial Agents

Nanotechnology is a promising science with new aspects to fight and prevent various diseases using nanomaterials. The capability expose the structure functions of biosystems at nanoscale level supports research leading development in biology, biotechnology, medicine, healthcare. This predominantly advantageous treating microbial infections as an alternative antibiotics. However, widespread production, use, misuse antibiotics have input next-generation alarm for emergence multiple-drug-resistant pathogenic bacteria. Due infectious from these drug-resistant strains, human mortality rates consistently increased are becoming epidemic our society. Consequently, there strong demand developing novel strategies materials that can cope problems. nanotechnology has created many antimicrobial options. small size nanomaterials suitable carrying out biological operations. Several metals metal oxides, such silver, copper, gold, zinc oxide, iron oxide nanoparticle types shown toxicity toward several microbes. Metal-based nanoparticles been broadly examined set biomedical applications. According World Health Organization, reduced selectivity metal-based bacteria established them be effective against pathogens causing concern. known nonspecific bacterial mechanisms, which not only make resistance by difficult, but also widen spectrum antibacterial activity. efficiency studies achieved so far revealed results both Gram-positive Gram-negative Here we discuss potential either treat or induce resistance. fundamental required focus on molecular mechanism activity